All Publications

Development and Content Validation of a Yoga-Based Spiritual Well-Being Scale

Praerna Chowdhury, Govindaraj Ramajayam, Arun Sasidharan, P. N. Ravindra, Bindu M. Kutty

Consciousness, Cognition, and Contemplative Sciences

Development and Validation of VIPASSANA Proficiency Scale

Ramajayam Govindaraji, Ratna Jyothi, Rahul Venugopal, Mariyamma Philip

Consciousness, Cognition, and Contemplative Sciences

Machine Learning Models for Emotion Prediction Using Eye-Gaze Features

Sharon Zachariah, Harshitha P G, Shreya Paul, Vishaka Biju, Meenakshi Malhotra, Deepshik Sharma

IEEE

Non-duality in brain and experience of advanced meditators-key role for intrinsic neural timescales

Malipeddi Saketh, Arun Sasidharan, Bianca Ventura, Rahul Venugopal, Clemens Christian Bauer, Prejaas K. B. Tewarie, Ravindra P. Nagendra, Seema Mehrotra, John P. John, Balachundhar Subramaniam, Steven Laureys, Bindu M. Kutty, Georg Northoff

Communications Biology

Sound-based Meditation Alters Brain Activity: EEG Evidence for Power Reduction and Enhanced Conscious Alertness

Km Megha, Ankita Mishra, Raksha Sharma, Pallabi Pal, Vijay Shanker Yadav, Arjun Ram Roja, Arun Sasidharan, Gulshan Kumar, Sanjib Patra

Annals of Neurosciences

Temporal EEG Signatures of Meditation Experience: Peak Brainwave Changes at 7 Minutes During Isha Yoga Breath Watching

Saketh, Malipeddi, Sasidharan, Arun, Venugopal, Rahul, Tewarie, Prejaas K.B., P Nagendra, Ravindra, Northoff, Georg, Laureys, Steven, Subramaniam, Balachundhar, Kutty, Bindu M

Mindfulness

The Neurodynamic Core of Meditation: Dissociating Meditation from Rest and Task in a Reliability-based EEG study

Praerna Chowdhury, Ramajayam Govindaraj, Arun Sasidharan, Apar A Saoji, Ravindra P N, Georg Northoff, Bindu M Kutty

bioRxiv

Ultra-short term Heart Rate Variability in moderate and severe Obstructive Sleep Apnea

Karthik Nagaraju, Kavitha Venkatnarayan, Rahul Venugopal, Ravindra P. Nagendra, Chitra Veluthat, Priya Ramachandran, Uma Devaraj, Uma Maheswari Krishnaswamy

Respiratory Medicine

Aging and MPTP sensitivity depend on molecular and ultrastructural signatures of astroglia and microglia in mice substantia nigra

P.L. Abhilash, U. Bharti, S.K. Rashmi, M. Philip et al.

Cellular and Molecular …

Cognitive Deficits in Persons with Functional Pain Syndrome: A Systematic Review

A. Tadpatrikar, V. Marigowda, M.K. Sharma et al.

Indian Journal of …

Eye Blink Artifact Removal from EEG Signals: A Comparative Analysis

Rohan S Parthasarathy, Rohith Prem Kumar, R Sunitha, Arun Sasidharan

2025 IEEE International Conference on Electronics, Computing and Communication Technologies (CONECCT)

Neurophysiological features of dream recall and the phenomenology of dreams: Auditory stimulation impacts dream experiences

Gulshan Kumar, S Naaz, N. Jabin, Arun Sasidharan et al.

Consciousness and …

Non-duality in brain and experience of advanced meditators–Key role for Intrinsic Neural Timescales

Saketh Malipeddi, Arun Sasidharan, B. Ventura, Rahul Venugopal et al.

bioRxiv

Personalized theta transcranial alternating current stimulation and gamma transcranial alternating current stimulation bring differential neuromodulatory

Rahul Venugopal, Arun Sasidharan, K. Bhowmick et al.

Neuromodulation …

Similar States, Different Paths: Neurodynamics of diverse meditation techniques

P. Shrimali, Arun Sasidharan, Saketh Malipeddi, B. Ventura et al.

bioRxiv

Time-to-onset and temporal dynamics of EEG during breath-watching meditation

Saketh Malipeddi, Arun Sasidharan, Rahul Venugopal, P.K.B. Tewarie et al.

bioRxiv

Delayed decompositional changes in indoor settings among Tibetan monastic communities in India: A case report

T.L. Tidwell, L.E. Eisenberg, A. Fedotov, E. Kokurina et al.

Forensic Science …

Development and Validation of a Culturally Adapted, Event-related Potential Paradigm for Assessing Alcohol Cue Reactivity and Error Processing in Alcohol Dependence

Anupa Arunkumar Shenoy, Samir Kumar Praharaj, Shweta Rai, Kirtana R. Nayak, Arun Sasidharan, Hari Prakash Palaniswamy, Chinmay Ajit Suryavanshi, Sumit Sharma, Umesh Shreekantiah, Vrinda Marigowda

Indian Journal of Psychological Medicine

Polysomnographic Evaluation of Sleep Disorders in Essential Tremor and Essential Tremor Plus: A Comparison With Healthy Controls

R.P. Singh, S. Mythirayee, D.V. Seshagiri et al.

Journal of …

Practice and Proficiency of Isha Yoga for Better Mental Health Outcomes: Insights from a COVID-19 Survey

Saketh Malipeddi, Seema Mehrotra, John P. John, Bindu M. Kutty

Frontiers in Public Health

Relaxed Alertness in Novice and Advanced Meditators – A Neurophysiological and Psychological Study of Isha Yoga Practices

Saketh Malipeddi, Arun Sasidharan, Ravindra P.N., Seema Mehrotra, John P. John, Bindu M. Kutty

Mindfulness

Restoration of sleep–wake behavior following short photoperiod exposure in ventral subicular lesioned male Wistar rats: A 24‐h sleep–wake

N. Prem, Arun Sasidharan, B.N. Srikumar et al.

Journal of …

The balanced mind and its intrinsic neural timescales in advanced meditators

Saketh Malipeddi, Arun Sasidharan, Rahul Venugopal, B. Ventura et al.

bioRxiv

Circadian rhythm manipulations: Implications on behavioral restoration in central nervous system insults

Subhadeep Dutta, B.N. Srikumar et al.

Sleep and Clocks in …

Conscious Experience of Self: An Ever Enchanting Phenomenon

Bindu M. Kutty, P.N. Ravindra

Journal of Applied Consciousness …

COVID-19 pandemic, sleep quality, and emotional tone of dreams: A model to look into how psychological stress affects sleep quality, dream and emotionality

Gulshan Kumar, P.S. Yadav et al.

Journal of Dream …

Development and Validation of Ayurveda Based Assessment Scale for Anxiety

Basavaraj R. Tubaki, G.S. Lavekar, C.R. Chandrashekar, T.N. Sathyaprabha, Bindu M. Kutty

Journal of Ayurveda and Integrative Medicine

Differences in Brain Connectivity of Meditators during Assessing Neurocognition via Gamified Experimental Logic Task: A Machine Learning Approach

Ashwini S. Savanth, P.A. Vijaya, Ajay Kumar Nair, Bindu Kutty

Neuroradiology Journal

Reversal of neuropsychiatric comorbidities in an animal model of temporal lobe epilepsy following systemic administration of dental pulp stem cells and bone marrow

S. Senthilkumar, K. Maiya, N.K. Jain, S. Mata et al.

Current gene …

Classification of Rajayoga Meditators Based on the Duration of Practice Using Graph Theoretical Measures of Functional Connectivity from Task-Based Functional Magnetic Resonance Imaging

Ashwini S. Savanth, P.A. Vijaya, Ajay Kumar Nair, Bindu M. Kutty

International Journal of Yoga

Differential effects of levetiracetam on hippocampal CA1 synaptic plasticity and molecular changes in the dentate gyrus in epileptic rats

Ratna Jyothi Salaka, K.P. Nair, R.B. Sasibhushana et al.

Neurochemistry …

Enhanced Dehydroepiandrosterone Levels are Positively Correlated with N3 Sleep Stage in Long-term Mindfulness Meditation Practitioners

Ravindra P. Nagendra, Talakad N. Sathyaprabha, Bindu M. Kutty

Sleep Science

Enriched Environment Rescues Impaired Sleep–Wake Architecture and Abnormal Neural Dynamics in Chronic Epileptic Rats

K.P. Nair, Ratna Jyothi Salaka, B.N. Srikumar, Bindu M. Kutty, B.S.S. Rao

Neuroscience

Ventral subicular lesion impairs pro-social empathy-like behavior in adult Wistar rats

Subhadeep Dutta, B.N. Srikumar, B.S.S. Rao, Bindu M. Kutty

Neuroscience letters

A proof-of-concept study of maternal immune activation mediated induction of Toll-like receptor (TLR) and inflammasome pathways leading to

P.M. Talukdar, F. Abdul, M. Maes, M. Berk et al.

European …

Drug addiction-How it hijacks our cognition &consciousness

Bindu M. Kutty

Indian Journal of Medical Research

Enriched environment ameliorates chronic temporal lobe epilepsy‐induced behavioral hyperexcitability and restores synaptic plasticity in CA3–CA1 synapses in male

Ratna Jyothi Salaka, K.P. Nair, K. Annamalai et al.

Journal of …

Exposure to short photoperiod regime restores spatial cognition in ventral subicular lesioned rats: potential role of hippocampal plasticity, glucocorticoid

Subhadeep Dutta, B.N. Srikumar et al.

Molecular …

Patients with Primary Cervical Dystonia have Significant Sleep Impairment and Polysomnographic Abnormalities

Somdattaa Ray, Gulshan Kumar, Bindu Kutty, Pramod K Pal, Ravi Yadav

Sleep and Vigilance

People with dyssomnia showed increased vulnerability to CoVID-19 pandemic - a questionnaire-based study exploring the patterns and predictors of sleep quality using the latent class analysis technique in Indian population

Arathi Radhakrishnan, Ramajayam Govindaraj, Arun Sasidharan, PN Ravindra, Ravi Yadav, Bindu M Kutty

Sleep medicine

Sleep and other Non-motor Symptoms in Patients with Idiopathic Oromandibular Dystonia and Meige Syndrome: A Questionnaire-based Study

Somdattaa Ray, Bindu Kutty, Pramod Kumar Pal, Ravi Yadav

Annals of Indian Academy of Neurology

Maternal immune activation causes schizophrenia-like behaviors in the offspring through activation of immune-inflammatory, oxidative and apoptotic

P.M. Talukdar, F. Abdul, M. Maes, V.S. Binu et al.

Molecular …

Meditation, well-being and cognition in heartfulness meditators – A pilot study

Bhuvnesh Sankar Sylapan, Ajay Kumar Nair, Krishnamurthy Jayanna, Saketh Mallipeddi, Sunil Sathyanarayana, Bindu M Kutty

Consciousness and Cognition

Remarkable migration propensity of dental pulp stem cells towards neurodegenerative milieu: an in vitro analysis

S. Senthilkumar, C. Venugopal, S. Parveen, K.S. Rai et al.

Neurotoxicology

Short photoperiod restores ventral subicular lesion‐induced deficits in affective and socio‐cognitive behavior in male Wistar rats

Subhadeep Dutta, B.N. Srikumar et al.

Journal of …

Admixing MPTP-resistant and MPTP-vulnerable mice enhances striatal field potentials and calbindin-D28K expression to avert motor behaviour deficits

D.J. Vidyadhara, Arun Sasidharan, Bindu M. Kutty et al.

Behavioural brain …

Effect of early maternal separation stress on attention, spatial learning and social interaction behaviour

M.Y. Kambali, K. Anshu, Bindu M. Kutty et al.

Experimental brain …

Schizophrenia patients show aberrant brain dynamics associated with gestalt-perception and corollary discharge: Reflections from ERP and fMRI findings

Arun Sasidharan, Ajay Kumar Nair, V. Marigowda, A. Lukose et al.

bioRxiv

Simultaneous assessment of P50, MMN, ERN and P300 event-related potentials among patients with Schizophrenia–an exploratory study

Arun Sasidharan, Ajay Kumar Nair, V. Marigowda, A. Lukose et al.

Biorxiv

Temporal lobe epilepsy-induced neurodegeneration and cognitive deficits: Implications for aging

M. Vrinda, S. Arun, B.N. Srikumar, Bindu M. Kutty et al.

Journal of chemical …

The impact of maternal separation and isolation stress during stress hyporesponsive period on fear retention and extinction recall memory from 5-week-to 1

P.K. Mishra, Bindu M. Kutty, T.R. Laxmi

Experimental Brain Research

Assessment of Sleep Spindle Density among Genetically Positive Spinocerebellar Ataxias Types 1, 2, and 3 Patients

Seshagiri DV, Raghasudha B, Arun Sasidharan, Pramod K Pal, Sanjeev Jain, Ravi Yadav, Bindu M Kutty

Annals of Neurosciences

Auditory verbal hallucinations in schizophrenia: a model for aberrant self-consciousness

John P. John, P. Parekh, Harsha N. Halahalli, S Menon et al.

Self, Culture and …

Beyond hypnograms - Assessing sleep stability using acoustic and electrical stimulation

Rahul Venugopal, Arun Sasidharan, Vrinda Marigowda, Gulshan Kumar, Ajay Kumar Nair, Sumit Sharma, Chetan Mukundan, Bindu M Kutty

Neuromodulation

Challenges in sleep stage R scoring in patients with autosomal dominant spinocerebellar ataxias (SCA1, SCA2 and SCA3) and oculomotor abnormalities - a whole night polysomnographic evaluation

Seshagiri DV, Arun Sasidharan, Gulshan Kumar, Pramod K Pal, Sanjeev jain, Bindu M Kutty, Ravi Yadav

Sleep Medicine

Dissociating meditation proficiency and experience dependent EEG changes during traditional Vipassana meditation practice

Ratna Jyothi Kakumanu, Ajay Kumar Nair, Rahul Venugopal, Arun Sasidharan, Prasanta Kumar Ghosh, John P John, Bindu M Kutty

Biological Psychology

Efficacy of the combination of cognitive training and acoustic stimulation in eliciting lucid dreams during undisturbed sleep - a pilot study using polysomnography, dream reports and questionnaires

Gulshan Kumar, Arun Sasidharan, Bindu M Kutty

International Journal of Dream Research

Meditation, Cognitive Reserve and the Neural Basis of Consciousness

Ajay Kumar Nair, Bindu M. Kutty

Interdisciplinary Convergences on Knowing and Being

Neuroprotection by human dental pulp mesenchymal stem cells: from billions to nano

C. Venugopal, S.K., K.S. Rai, V.B. Pinnelli et al.

Current gene …

State-trait influences of Vipassana meditation practice on P3 EEG dynamics

Ratna Jyothi, Ajay Kumar Nair, Arun Sasidharan, John P John, Seema Mehrotra, Ravindra Panth, Bindu M Kutty

Progress in brain research

What contributes to wellbeing gains – proficiency or duration of meditation related practices?

Ajay Kumar Nair, John P John, Seema Mehrotra, Bindu M Kutty

International Journal of Wellbeing

Altered attentional processing in male and female rats in a prenatal valproic acid exposure model of autism spectrum disorder

K. Anshu, Ajay Kumar Nair, U.D. Kumaresan, Bindu M. Kutty et al.

Autism …

Elevated serum adenosine deaminase levels in neuroleptic-naïve patients with recent-onset schizophrenia

Arun Sasidharan, Ajay Kumar Nair, John P John, Philip M, Sarada Subramanian, Sanjeev Jain, Bindu M Kutty

Asian Journal of Psychiatry

Enriched environment attenuates behavioral seizures and depression in chronic temporal lobe epilepsy

M. Vrinda, Arun Sasidharan, S. Aparna, B.N. Srikumar et al.

Exposure to short photoperiod regime reduces ventral subicular lesion-induced anxiety-like behavior in Wistar rats

Subhadeep Dutta, B.N. Srikumar, B.S.S. Rao, Bindu M. Kutty

Physiology &behavior

Further evidences for sleep instability and impaired spindle-delta dynamics in schizophrenia - a whole-night polysomnography study with neuroloop-gain and sleep-cycle analysis

Arun Sasidharan, Ajay Kumar Nair, Amuu K Lukose, Vrinda Marigowda, John P John, Bindu M Kutty

Sleep Medicine

Just a minute meditation - Rapid voluntary conscious state shifts in long term meditators

Ajay Kumar Nair, Arun Sasidharan, John P John, Seema Mehrotra, Bindu M Kutty

Consciousness and Cognition

Vipassana Meditation Practices Enhance the Parasympathetic Activity during Sleep - a Case-Control Study of Heart Rate Variability across Sleep Cycles

Ravindra P Nagendra, Sathiamma Sulekha, Arun Sasidharan, Sathyaprabha TN, Nithyanda Pradhan, Raju TR, Bindu M Kutty

International journal of complementary and alternative medicine

Assessing Neurocognition via Gamified Experimental Logic - A Novel Approach to Simultaneous Acquisition of Multiple ERPs

Ajay Kumar Nair, Arun Sasidharan, John P John, Seema Mehrotra, Bindu M Kutty

Frontiers in Neuroscience

Long term exposure to combination paradigm of environmental enrichment, physical exercise and diet reverses the spatial memory deficits and restores

V. Kapgal, N. Prem, P. Hegde, T.R. Laxmi et al.

Neurobiology of Learning …

Manasamitra Vataka and Shirodhara treatments preserve slow wave sleep and promote sleep continuity in patients with generalized anxiety disorder and co-morbid generalized social phobia

Basavaraj Tubaki, Anupriya Verma, Arun Sasidharan, Sulekha Srikumar, TN Sathyaprabha, D Sudhakar, CR Chandrashekar, GS Lavekar, Bindu M Kutty

Current Science

Senior Vipassana Meditation practitioners exhibit distinct REM sleep organization from that of novice meditators and healthy controls

Nirmala Maruthai, Ravindra PN, Arun Sasidharan, Sulekha Srikumar, Karuna Datta, Sunao Uchida, Bindu M Kutty

International Review of Psychiatry

Serotonin and Melatonin vis-à-vis Sleep Disorders

Ravindra P. Nagendra, Bindu M. Kutty

Serotonin and Melatonin

The neuroprotective effect of dark chocolate in monosodium glutamate-induced nontransgenic Alzheimer disease model rats: biochemical, behavioral, and

S. Madhavadas, V.K. Kapgal, Bindu M. Kutty et al.

Journal of dietary …

Endogenous-cue prospective memory involving incremental updating of working memory - an fMRI study

Harsha Halahalli, John P John, Ammu K lukose, Sanjeev Jain, Bindu M Kutty

Brain Structure and Function

A study on fear memory retrieval and REM sleep in maternal separation and isolation stressed rats

D. Sampath, K.R. Sabitha, P. Hegde et al.

Behavioural brain …

Amyloid beta lowering and cognition enhancing effects of ghrelin receptor analog [D-Lys (3)] GHRP-6 in rat model of obesity

S. Madhavadas, Bindu M. Kutty et al.

Indian journal of …

Cholinergic immunotoxin 192 IgG-SAPORIN alters subicular theta–gamma activity and impairs spatial learning in rats

S. Rastogi, S. Unni, S. Sharma, T.R. Laxmi et al.

Neurobiology of Learning …

Current understanding on the neurobiology of sleep and wakefulness

Arun Sasidharan, Sulekha Srikumar, Bindu M Kutty

International Journal of Clinical and Experimental Physiology

Effect of Yoga on migraine: A comprehensive study using clinical profile and cardiac autonomic functions

R. Kisan, M.U. Sujan, M. Adoor, R Rao et al.

journal of yoga

Exploration of the effect of demographic and clinical confounding variables on results of voxel-based morphometric analysis in schizophrenia

A.A. Vijayakumari, P. Thirunavukkarasu et al.

Artificial Intelligence and …

Fractal dimension for drowsiness detection in brainwaves

M. Pavithra, B. Niranjana Krupa et al.

and informatics (IC3I …

Images in electroconvulsive therapy: ECS dose-dependently increases cell proliferation in the subgranular region of the rat hippocampus

J.S.M. Smitha, R. Roopa, B.K.C. Sagar, Bindu M. Kutty et al.

The Journal of …

Images in electroconvulsive therapy: electroconvulsive shocks dose-dependently increase dendritic arborization in the CA1 region of the rat hippocampus

J.S.M. Smitha, R. Roopa, N Khaleel, Bindu M. Kutty et al.

The journal of …

Clinical Efficacy of Manasamitra Vataka (an Ayurveda Medication) on Generalized Anxiety Disorder with Comorbid Generalized Social Phobia - A Randomized Controlled Study

Basavaraj Tubaki, CR Chandrashekar, D Sudhakar, TNS Prabha, Lavekar GS, Bindu M Kutty

The Journal of Alternative and Complementary Medicine

Functional importance of sleep - An overview

Ravindra PN, Bindu M Kutty

Indian Journal of Sleep Medicine

Meditation and its regulatory role on sleep

Ravindra PN, Nirmala Maruthai, Bindu M Kutty

Frontiers in Neurology

Olfactory tract transection in neonatal rats: evidence for mitral cell regeneration and restoration of functional connectivity with its targets

S.P. Anil, T.R. Laxmi, Bindu M. Kutty, T.R. Raju

Indian Journal of …

Chronic stress-induced changes in REM sleep on theta oscillations in the rat hippocampus and amygdala

P. Hegde, H.R. Jayakrishnan, S. Chattarji, Bindu M. Kutty et al.

Brain research

NIH-3T3 fibroblast transplants enhance host regeneration and improve spatial learning in ventral subicular lesioned rats

J. Rekha, L.R. Veena, N. Prem, P Kalaivani et al.

Behavioural brain …

Case series of three children and adolescents with periodic hypersomnia

V. H.R., V. Danivas, Bindu M. Kutty et al.

Journal of Indian …

Long-term effects of early maternal separation and isolation stress on adulthood behaviour of female rats

D. Sampath, S. Vaishnavi, R. Durgalakshmi, Bindu M. Kutty et al.

Current Science

New vistas in treating diabetes-Insight into a holistic approach

Bindu M. Kutty, T.R. Raju

Indian Journal of Medical Research

Practitioners of vipassana meditation exhibit enhanced slow wave sleep and REM sleep states across different age groups

Ravindra PN, Sulekha Srikumar, TN Sathyaprabha, Nityananda Pradhan, TR Raju, Bindu M Kutty

Sleep and Biological Rhythms

Transplantation of hippocampal cell lines restore spatial learning in rats with ventral subicular lesions

J. Rekha, S Chakravarthy, L.R. Veena et al.

Behavioral …

Exposure to enriched environment improves spatial learning performances and enhances cell density but not choline acetyltransferase activity in the hippocampus of

A. Dhanushkodi, B. Bindu, T.R. Raju et al.

Behavioral …

Evaluation of sleep architecture in practitioners of Sudarshan Kriya yoga and Vipassana meditation

Sulekha S, Thennarasu K, Appajachar Vedamurthachar, TR Raju, Bindu M Kutty

Sleep and Biological Rhythms

Post insult enriched housing improves the 8-arm radial maze performance but not the Morris water maze task in ventral subicular lesioned rats

B. Bindu, J. Rekha, Bindu M. Kutty

Brain Research

Selective neurodegeneration of hippocampus and entorhinal cortex correlates with spatial learning impairments in rats with bilateral ibotenate lesions of

L. Devi, L. Diwakar, T.R. Raju, Bindu M. Kutty

Brain Research